diff options
Diffstat (limited to 'man/saem.Rd')
| -rw-r--r-- | man/saem.Rd | 13 |
1 files changed, 10 insertions, 3 deletions
diff --git a/man/saem.Rd b/man/saem.Rd index fd19fe59..5a125ab6 100644 --- a/man/saem.Rd +++ b/man/saem.Rd @@ -22,6 +22,7 @@ saem(object, ...) omega.init = "auto", covariates = NULL, covariate_models = NULL, + center_covariates = c(NA, "median", "mean"), no_random_effect = NULL, error.init = c(1, 1), nbiter.saemix = c(300, 100), @@ -101,6 +102,10 @@ initialisation of \link[saemix:saemixModel]{saemix::saemixModel} is used for ome variable, i.e. of the type 'parameter ~ covariate'. Covariates must be available in the 'covariates' data frame.} +\item{center_covariates}{Either NA, for no centering, or your +preferred function for calculating the center, currently either +median or mean.} + \item{no_random_effect}{Character vector of degradation parameters for which there should be no variability over the groups. Only used if the covariance model is not explicitly specified.} @@ -199,9 +204,11 @@ print(f_saem_dfop_sfo) plot(f_saem_dfop_sfo) summary(f_saem_dfop_sfo, data = TRUE) -# The following takes about 6 minutes -f_saem_dfop_sfo_deSolve <- saem(f_mmkin["DFOP-SFO", ], solution_type = "deSolve", - nbiter.saemix = c(200, 80)) +# The following took about 6 minutes and currently fails with +# "Error in deSolve::lsoda(y = odeini, times = outtimes_deSolve, func = lsoda_func, : +# illegal input detected before taking any integration steps - see written message" +#f_saem_dfop_sfo_deSolve <- saem(f_mmkin["DFOP-SFO", ], solution_type = "deSolve", +# nbiter.saemix = c(200, 80)) #anova( # f_saem_dfop_sfo, |