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the kinetic model with first-order terms for a two-way transfer from a free
to a bound fraction, and a first-order degradation term for the free
fraction. The initial condition is a defined amount in the free fraction
and no substance in the bound fraction."><meta name="robots" content="noindex"><!-- mathjax --><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script><script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script><!--[if lt IE 9]>
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<h1>Single First-Order Reversible Binding kinetics</h1>
<small class="dont-index">Source: <a href="https://github.com/jranke/mkin/blob/HEAD/R/parent_solutions.R" class="external-link"><code>R/parent_solutions.R</code></a></small>
<div class="hidden name"><code>SFORB.solution.Rd</code></div>
</div>
<div class="ref-description">
<p>Function describing the solution of the differential equations describing
the kinetic model with first-order terms for a two-way transfer from a free
to a bound fraction, and a first-order degradation term for the free
fraction. The initial condition is a defined amount in the free fraction
and no substance in the bound fraction.</p>
</div>
<div id="ref-usage">
<div class="sourceCode"><pre class="sourceCode r"><code><span><span class="fu">SFORB.solution</span><span class="op">(</span><span class="va">t</span>, <span class="va">parent_0</span>, <span class="va">k_12</span>, <span class="va">k_21</span>, <span class="va">k_1output</span><span class="op">)</span></span></code></pre></div>
</div>
<div id="arguments">
<h2>Arguments</h2>
<dl><dt>t</dt>
<dd><p>Time.</p></dd>
<dt>parent_0</dt>
<dd><p>Starting value for the response variable at time zero.</p></dd>
<dt>k_12</dt>
<dd><p>Kinetic constant describing transfer from free to bound.</p></dd>
<dt>k_21</dt>
<dd><p>Kinetic constant describing transfer from bound to free.</p></dd>
<dt>k_1output</dt>
<dd><p>Kinetic constant describing degradation of the free
fraction.</p></dd>
</dl></div>
<div id="value">
<h2>Value</h2>
<p>The value of the response variable, which is the sum of free and
bound fractions at time <code>t</code>.</p>
</div>
<div id="references">
<h2>References</h2>
<p>FOCUS (2006) “Guidance Document on Estimating Persistence
and Degradation Kinetics from Environmental Fate Studies on Pesticides in
EU Registration” Report of the FOCUS Work Group on Degradation Kinetics,
EC Document Reference Sanco/10058/2005 version 2.0, 434 pp,
<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a>
FOCUS (2014) “Generic guidance for Estimating Persistence
and Degradation Kinetics from Environmental Fate Studies on Pesticides in
EU Registration” Report of the FOCUS Work Group on Degradation Kinetics,
Version 1.1, 18 December 2014
<a href="http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics" class="external-link">http://esdac.jrc.ec.europa.eu/projects/degradation-kinetics</a></p>
</div>
<div id="see-also">
<h2>See also</h2>
<div class="dont-index"><p>Other parent solutions:
<code><a href="DFOP.solution.html">DFOP.solution</a>()</code>,
<code><a href="FOMC.solution.html">FOMC.solution</a>()</code>,
<code><a href="HS.solution.html">HS.solution</a>()</code>,
<code><a href="IORE.solution.html">IORE.solution</a>()</code>,
<code><a href="SFO.solution.html">SFO.solution</a>()</code>,
<code><a href="logistic.solution.html">logistic.solution</a>()</code></p></div>
</div>
<div id="ref-examples">
<h2>Examples</h2>
<div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span></span></span>
<span class="r-in"><span> <span class="fu"><a href="https://rdrr.io/r/graphics/plot.default.html" class="external-link">plot</a></span><span class="op">(</span><span class="kw">function</span><span class="op">(</span><span class="va">x</span><span class="op">)</span> <span class="fu">SFORB.solution</span><span class="op">(</span><span class="va">x</span>, <span class="fl">100</span>, <span class="fl">0.5</span>, <span class="fl">2</span>, <span class="fl">3</span><span class="op">)</span>, <span class="fl">0</span>, <span class="fl">2</span><span class="op">)</span></span></span>
<span class="r-plt img"><img src="SFORB.solution-1.png" alt="" width="700" height="433"></span>
<span class="r-in"><span></span></span>
</code></pre></div>
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