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    <h1>Create a time series of decline data</h1>
    <small class="dont-index">Source: <a href='https://github.com/jranke/pfm/blob/master/R/twa.R'><code>R/twa.R</code></a></small>
    <div class="hidden name"><code>one_box.Rd</code></div>
    </div>

    <div class="ref-description">
    
    <p>Create a time series of decline data</p>
    
    </div>

    <pre class="usage"><span class='fu'>one_box</span>(<span class='no'>x</span>, <span class='no'>ini</span>, <span class='no'>...</span>, <span class='kw'>t_end</span> <span class='kw'>=</span> <span class='fl'>100</span>, <span class='kw'>res</span> <span class='kw'>=</span> <span class='fl'>0.01</span>)

<span class='co'># S3 method for numeric</span>
<span class='fu'>one_box</span>(<span class='no'>x</span>, <span class='kw'>ini</span> <span class='kw'>=</span> <span class='fl'>1</span>, <span class='no'>...</span>, <span class='kw'>t_end</span> <span class='kw'>=</span> <span class='fl'>100</span>, <span class='kw'>res</span> <span class='kw'>=</span> <span class='fl'>0.01</span>)

<span class='co'># S3 method for character</span>
<span class='fu'>one_box</span>(<span class='no'>x</span>, <span class='kw'>ini</span> <span class='kw'>=</span> <span class='fl'>1</span>, <span class='no'>parms</span>, <span class='no'>...</span>, <span class='kw'>t_end</span> <span class='kw'>=</span> <span class='fl'>100</span>,
  <span class='kw'>res</span> <span class='kw'>=</span> <span class='fl'>0.01</span>)

<span class='co'># S3 method for mkinfit</span>
<span class='fu'>one_box</span>(<span class='no'>x</span>, <span class='kw'>ini</span> <span class='kw'>=</span> <span class='st'>"model"</span>, <span class='no'>...</span>, <span class='kw'>t_end</span> <span class='kw'>=</span> <span class='fl'>100</span>, <span class='kw'>res</span> <span class='kw'>=</span> <span class='fl'>0.01</span>)</pre>
    
    <h2 class="hasAnchor" id="arguments"><a class="anchor" href="#arguments"></a>Arguments</h2>
    <table class="ref-arguments">
    <colgroup><col class="name" /><col class="desc" /></colgroup>
    <tr>
      <th>x</th>
      <td><p>When numeric, this is the half-life to be used for an exponential
decline. When a character string specifying a parent decline model is given
e.g. <code>FOMC</code>, <code>parms</code> must contain the corresponding paramters.
If x is an <code>mkinfit</code> object, the decline is calculated from this
object.</p></td>
    </tr>
    <tr>
      <th>ini</th>
      <td><p>The initial amount. If x is an <code>mkinfit</code> object, and
ini is 'model', the fitted initial concentrations are used. Otherwise, ini
must be numeric. If it has length one, it is used for the parent and
initial values of metabolites are zero, otherwise, it must give values for
all observed variables.</p></td>
    </tr>
    <tr>
      <th>...</th>
      <td><p>Further arguments passed to methods</p></td>
    </tr>
    <tr>
      <th>t_end</th>
      <td><p>End of the time series</p></td>
    </tr>
    <tr>
      <th>res</th>
      <td><p>Resolution of the time series</p></td>
    </tr>
    <tr>
      <th>parms</th>
      <td><p>A named numeric vector containing the model parameters</p></td>
    </tr>
    </table>
    
    <h2 class="hasAnchor" id="value"><a class="anchor" href="#value"></a>Value</h2>

    <p>An object of class <code>one_box</code>, inheriting from <code>ts</code>.</p>
    

    <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
    <pre class="examples"><div class='input'><span class='co'># Only use a half-life</span>
<span class='no'>pred_0</span> <span class='kw'>&lt;-</span> <span class='fu'>one_box</span>(<span class='fl'>10</span>)
<span class='fu'>plot</span>(<span class='no'>pred_0</span>)</div><div class='img'><img src='one_box-1.png' alt='' width='700' height='433' /></div><div class='input'>
<span class='co'># Use a fitted mkinfit model</span>
<span class='fu'>require</span>(<span class='no'>mkin</span>)
<span class='no'>fit</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='http://www.rdocumentation.org/packages/mkin/topics/mkinfit'>mkinfit</a></span>(<span class='st'>"FOMC"</span>, <span class='no'>FOCUS_2006_C</span>, <span class='kw'>quiet</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>)
<span class='no'>pred_1</span> <span class='kw'>&lt;-</span> <span class='fu'>one_box</span>(<span class='no'>fit</span>)
<span class='fu'>plot</span>(<span class='no'>pred_1</span>)</div><div class='img'><img src='one_box-2.png' alt='' width='700' height='433' /></div><div class='input'>
<span class='co'># Use a model with more than one observed variable</span>
<span class='no'>m_2</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='http://www.rdocumentation.org/packages/mkin/topics/mkinmod'>mkinmod</a></span>(<span class='kw'>parent</span> <span class='kw'>=</span> <span class='fu'><a href='http://www.rdocumentation.org/packages/mkin/topics/mkinsub'>mkinsub</a></span>(<span class='st'>"SFO"</span>, <span class='st'>"m1"</span>), <span class='kw'>m1</span> <span class='kw'>=</span> <span class='fu'><a href='http://www.rdocumentation.org/packages/mkin/topics/mkinsub'>mkinsub</a></span>(<span class='st'>"SFO"</span>))</div><div class='output co'>#&gt; <span class='message'>Successfully compiled differential equation model from auto-generated C code.</span></div><div class='input'><span class='no'>fit_2</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='http://www.rdocumentation.org/packages/mkin/topics/mkinfit'>mkinfit</a></span>(<span class='no'>m_2</span>, <span class='no'>FOCUS_2006_D</span>, <span class='kw'>quiet</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>)
<span class='no'>pred_2</span> <span class='kw'>&lt;-</span> <span class='fu'>one_box</span>(<span class='no'>fit_2</span>, <span class='kw'>ini</span> <span class='kw'>=</span> <span class='st'>"model"</span>)
<span class='fu'>plot</span>(<span class='no'>pred_2</span>)</div><div class='img'><img src='one_box-3.png' alt='' width='700' height='433' /></div></pre>
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      <li><a href="#arguments">Arguments</a></li>
      
      <li><a href="#value">Value</a></li>
      
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