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-rw-r--r--man/pfm_degradation.Rd27
1 files changed, 26 insertions, 1 deletions
diff --git a/man/pfm_degradation.Rd b/man/pfm_degradation.Rd
index 81f2e81..163bcee 100644
--- a/man/pfm_degradation.Rd
+++ b/man/pfm_degradation.Rd
@@ -28,11 +28,36 @@ is calculated (SFO model).}
\item{times}{The output times}
}
+\value{
+A data frame containing the output times and the concentrations
+assuming initial concentrations of 1 for the parent and zero for
+metabolites, if any.
+}
\description{
Calculate a time course of relative concentrations based on an mkinmod model
}
\examples{
-head(pfm_degradation("SFO", DT50 = 10))
+# Simple example of an SFO decline curve
+sfo_out <- pfm_degradation("SFO", DT50 = 10)
+head(sfo_out)
+
+# Fictive example with a metabolite where we first generate an SFO-SFO model
+sfo_sfo <- mkinmod(
+ parent = mkinsub("SFO", to = "metabolite"),
+ metabolite = mkinsub("SFO"))
+
+sfo_sfo_out <- pfm_degradation(sfo_sfo,
+ parms = c(k_parent = 0.1, f_parent_to_metabolite = 0.5, k_metabolite = 0.02))
+
+plot(
+ sfo_sfo_out[, "time"],
+ sfo_sfo_out[, "parent"], type = "l",
+ xlab = "Time", ylab = "Relative concentration",
+ xlim = c(0, 100))
+lines(
+ sfo_sfo_out[, "time"],
+ sfo_sfo_out[, "metabolite"], lty = 2)
+
}
\author{
Johannes Ranke

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