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Diffstat (limited to 'man/pfm_degradation.Rd')
| -rw-r--r-- | man/pfm_degradation.Rd | 27 |
1 files changed, 26 insertions, 1 deletions
diff --git a/man/pfm_degradation.Rd b/man/pfm_degradation.Rd index 81f2e81..163bcee 100644 --- a/man/pfm_degradation.Rd +++ b/man/pfm_degradation.Rd @@ -28,11 +28,36 @@ is calculated (SFO model).} \item{times}{The output times} } +\value{ +A data frame containing the output times and the concentrations +assuming initial concentrations of 1 for the parent and zero for +metabolites, if any. +} \description{ Calculate a time course of relative concentrations based on an mkinmod model } \examples{ -head(pfm_degradation("SFO", DT50 = 10)) +# Simple example of an SFO decline curve +sfo_out <- pfm_degradation("SFO", DT50 = 10) +head(sfo_out) + +# Fictive example with a metabolite where we first generate an SFO-SFO model +sfo_sfo <- mkinmod( + parent = mkinsub("SFO", to = "metabolite"), + metabolite = mkinsub("SFO")) + +sfo_sfo_out <- pfm_degradation(sfo_sfo, + parms = c(k_parent = 0.1, f_parent_to_metabolite = 0.5, k_metabolite = 0.02)) + +plot( + sfo_sfo_out[, "time"], + sfo_sfo_out[, "parent"], type = "l", + xlab = "Time", ylab = "Relative concentration", + xlim = c(0, 100)) +lines( + sfo_sfo_out[, "time"], + sfo_sfo_out[, "metabolite"], lty = 2) + } \author{ Johannes Ranke |
