aboutsummaryrefslogblamecommitdiff
path: root/docs/reference/IM1xIPC81.html
blob: bd9211c4afc0e1a2fcf32249add8f11fe2ccb3cb (plain) (tree)
1
2
3
4
5
6
7
8
9
10

                                                  
                






                                                                                                                            
 
               
                                                                                                                                                                                 

                  


                                                                                                                                                                                                             

                           

                                                                                                                                                                                                       
 
                     
                                                                                                                                                                                          
 


                                                                                                                                                                                            
 

                                             
                                     


 
 
                                                                                                                                          










                                                                                                    


 
 
                

                                                                                                                                                                                                    






                                                                               
 







                                                                            

                                                                                                                               



                                      

                                                             
                                                                                                                                     
             
          
 


                                                      
                          
                                                  



      


                                                 


                                              
      




                                
 

               
                 


                                                                                                  

                                                            

          
                                 









                                                                  
          
 


                                                                                                                                            


                                                                                      
                                                                                     
                                                  







                                                                                      

                                                                                            
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             







                                                                                                                                                                                                                                                                                                                           
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      







                                                                                                                            
                                                                                                                                                                                                                                                                                                                     















                                                                                    
                                                                                                                                                                                                                                                                                                                                                                                                                    





























                                                                                     
                                           
                                           





                                               
 





                                     
                                                                                




               

  
 

         
 
 
<!-- Generated by pkgdown: do not edit by hand -->
<!DOCTYPE html>
<html lang="en">
  <head>
  <meta charset="utf-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0">

<title>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells — IM1xIPC81 • drfit</title>


<!-- jquery -->
<script src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.3.1/jquery.min.js" integrity="sha256-FgpCb/KJQlLNfOu91ta32o/NMZxltwRo8QtmkMRdAu8=" crossorigin="anonymous"></script>
<!-- Bootstrap -->

<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.3.7/css/bootstrap.min.css" integrity="sha256-916EbMg70RQy9LHiGkXzG8hSg9EdNy97GazNG/aiY1w=" crossorigin="anonymous" />

<script src="https://cdnjs.cloudflare.com/ajax/libs/twitter-bootstrap/3.3.7/js/bootstrap.min.js" integrity="sha256-U5ZEeKfGNOja007MMD3YBI0A3OSZOQbeG6z2f2Y0hu8=" crossorigin="anonymous"></script>

<!-- Font Awesome icons -->
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.7.1/css/all.min.css" integrity="sha256-nAmazAk6vS34Xqo0BSrTb+abbtFlgsFK7NKSi6o7Y78=" crossorigin="anonymous" />
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.7.1/css/v4-shims.min.css" integrity="sha256-6qHlizsOWFskGlwVOKuns+D1nB6ssZrHQrNj1wGplHc=" crossorigin="anonymous" />

<!-- clipboard.js -->
<script src="https://cdnjs.cloudflare.com/ajax/libs/clipboard.js/2.0.4/clipboard.min.js" integrity="sha256-FiZwavyI2V6+EXO1U+xzLG3IKldpiTFf3153ea9zikQ=" crossorigin="anonymous"></script>

<!-- headroom.js -->
<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.9.4/headroom.min.js" integrity="sha256-DJFC1kqIhelURkuza0AvYal5RxMtpzLjFhsnVIeuk+U=" crossorigin="anonymous"></script>
<script src="https://cdnjs.cloudflare.com/ajax/libs/headroom/0.9.4/jQuery.headroom.min.js" integrity="sha256-ZX/yNShbjqsohH1k95liqY9Gd8uOiE1S4vZc+9KQ1K4=" crossorigin="anonymous"></script>

<!-- pkgdown -->
<link href="../pkgdown.css" rel="stylesheet">
<script src="../pkgdown.js"></script>




<meta property="og:title" content="Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells — IM1xIPC81" />
<meta property="og:description" content="This is the raw data documenting the influence of the alkyl
  chain length in 3 position on the toxicity to the
  promyelocytic leukemia rat cell line IPC-81. The substances
  are named according to the UFT naming scheme of these
  substances. IM13 BF4 means 1-methyl-3-propylimidazolium
  tetrafluoroborate, IM14 BF4 means
  1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10
  BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
  This is a subset (only the BF4 anion) of the data
  shown in Figure 3 in Ranke et al. (2004)." />
<meta name="twitter:card" content="summary" />




<!-- mathjax -->
<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/MathJax.js" integrity="sha256-nvJJv9wWKEm88qvoQl9ekL2J+k/RWIsaSScxxlsrv8k=" crossorigin="anonymous"></script>
<script src="https://cdnjs.cloudflare.com/ajax/libs/mathjax/2.7.5/config/TeX-AMS-MML_HTMLorMML.js" integrity="sha256-84DKXVJXs0/F8OTMzX4UR909+jtl4G7SPypPavF+GfA=" crossorigin="anonymous"></script>

<!--[if lt IE 9]>
<script src="https://oss.maxcdn.com/html5shiv/3.7.3/html5shiv.min.js"></script>
<script src="https://oss.maxcdn.com/respond/1.4.2/respond.min.js"></script>
<![endif]-->



  </head>

  <body>
    <div class="container template-reference-topic">
      <header>
      <div class="navbar navbar-default navbar-fixed-top" role="navigation">
  <div class="container">
    <div class="navbar-header">
      <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false">
        <span class="sr-only">Toggle navigation</span>
        <span class="icon-bar"></span>
        <span class="icon-bar"></span>
        <span class="icon-bar"></span>
      </button>
      <span class="navbar-brand">
        <a class="navbar-link" href="../index.html">drfit</a>
        <span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">0.7.3</span>
      </span>
    </div>

    <div id="navbar" class="navbar-collapse collapse">
      <ul class="nav navbar-nav">
        <li>
  <a href="../index.html">
    <span class="fas fa fas fa-home fa-lg"></span>
     
  </a>
</li>
<li>
  <a href="../reference/index.html">Reference</a>
</li>
      </ul>
      <ul class="nav navbar-nav navbar-right">
        
      </ul>
      
    </div><!--/.nav-collapse -->
  </div><!--/.container -->
</div><!--/.navbar -->

      

      </header>

<div class="row">
  <div class="col-md-9 contents">
    <div class="page-header">
    <h1>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells</h1>
    
    <div class="hidden name"><code>IM1xIPC81.Rd</code></div>
    </div>

    <div class="ref-description">
    <p>This is the raw data documenting the influence of the alkyl
  chain length in 3 position on the toxicity to the
  promyelocytic leukemia rat cell line IPC-81. The substances
  are named according to the UFT naming scheme of these
  substances. IM13 BF4 means 1-methyl-3-propylimidazolium
  tetrafluoroborate, IM14 BF4 means
  1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10
  BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
  This is a subset (only the BF4 anion) of the data
  shown in Figure 3 in Ranke et al. (2004).</p>
    </div>

    <pre class="usage"><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span>(<span class='no'>IM1xIPC81</span>)</pre>


    <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>

    <p>A dataframe containing the data as required for the
  <code><a href='drfit.html'>drfit</a></code> function. An additional column contains
  the tested organism (name of the cell line).</p>
    <h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2>

    <p>Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J,
  Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004)
  Biological effects of imidazolium ionic liquids with varying
  chain lenghts in acute Vibrio fischeri and WST-1 cell
  viability assays. Ecotoxicology and Environmental Safety
  58(3) 396-404</p>

    <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
    <pre class="examples"><div class='input'>  <span class='no'>rIM1xIPC81</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drfit.html'>drfit</a></span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='input'>
  <span class='no'>rIM1xIPC81.drc</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drcfit.html'>drcfit</a></span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='input'>
  <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span>(<span class='no'>rIM1xIPC81</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#&gt;    Substance ndl   n     lld   lhd    mtype logED50  2.5%  97.5%   unit  sigma
#&gt; 1   IM13 BF4   9  81  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 2   IM14 BF4  20 216 -0.0103 3.176   no fit      NA    NA     NA microM     NA
#&gt; 3   IM15 BF4   9 135  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 4   IM16 BF4   9 108  0.5918 3.000 inactive      NA    NA     NA microM     NA
#&gt; 5   IM17 BF4   9  81  0.5918 3.000 linlogit  2.5786 2.506 2.6617 microM 0.2376
#&gt; 6   IM18 BF4   9 135  0.5918 3.000 linlogit  1.6806 1.623 1.7419 microM 0.2325
#&gt; 7   IM19 BF4   9  81  0.5918 3.000 linlogit  1.6496 1.598 1.7031 microM 0.1453
#&gt; 8 IM1-10 BF4  11 162 -0.0103 3.000 linlogit  0.7697 0.687 0.8544 microM 0.2988
#&gt;        a     b       c    ED50 ED50 2.5% ED50 97.5%   EDx10
#&gt; 1     NA    NA      NA      NA        NA         NA      NA
#&gt; 2     NA    NA      NA      NA        NA         NA      NA
#&gt; 3     NA    NA      NA      NA        NA         NA      NA
#&gt; 4     NA    NA      NA      NA        NA         NA      NA
#&gt; 5 2.5786 2.300 0.01468 378.941   320.424    458.918 230.782
#&gt; 6 1.6806 2.237 0.05719  47.930    41.973     55.194  27.367
#&gt; 7 1.6496 1.977 0.10956  44.628    39.671     50.483  23.031
#&gt; 8 0.7697 1.936 0.45809   5.884     4.864      7.152   2.835</div><div class='input'>  <span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span>(<span class='no'>rIM1xIPC81.drc</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#&gt;    Substance ndl   n     lld   lhd    mtype logED50   2.5%  97.5%   unit  sigma
#&gt; 1   IM13 BF4   9  81  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 2   IM14 BF4  20 216 -0.0103 3.176 linlogit      NA     NA     NA microM 0.1529
#&gt; 3   IM15 BF4   9 135  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 4   IM16 BF4   9 108  0.5918 3.000 inactive      NA     NA     NA microM     NA
#&gt; 5   IM17 BF4   9  81  0.5918 3.000 linlogit  2.5786 2.4935 2.6497 microM 0.2376
#&gt; 6   IM18 BF4   9 135  0.5918 3.000 linlogit  1.6806 1.6168 1.7362 microM 0.2325
#&gt; 7   IM19 BF4   9  81  0.5918 3.000 linlogit  1.6496 1.5940 1.6990 microM 0.1453
#&gt; 8 IM1-10 BF4  11 162 -0.0103 3.000 linlogit  0.7697 0.6774 0.8458 microM 0.2988
#&gt;           a      b          c    ED50 ED50 2.5% ED50 97.5%   EDx10 EDx10 2.5%
#&gt; 1        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 2 5.390e+15 0.3148 -0.0001736      NA        NA         NA      NA         NA
#&gt; 3        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 4        NA     NA         NA      NA        NA         NA      NA         NA
#&gt; 5 1.281e+02 2.3001  0.0146821 378.964   311.555    446.372 230.790    202.915
#&gt; 6 2.079e+01 2.2373  0.0571925  47.930    41.382     54.478  27.367     23.809
#&gt; 7 1.342e+01 1.9773  0.1094542  44.630    39.260     50.000  23.036     20.614
#&gt; 8 2.258e+00 1.9362  0.4580784   5.884     4.758      7.011   2.835      2.181
#&gt;   EDx10 97.5%
#&gt; 1          NA
#&gt; 2          NA
#&gt; 3          NA
#&gt; 4          NA
#&gt; 5     258.665
#&gt; 6      30.925
#&gt; 7      25.459
#&gt; 8       3.489</div></pre>
  </div>
  <div class="col-md-3 hidden-xs hidden-sm" id="sidebar">
    <h2>Contents</h2>
    <ul class="nav nav-pills nav-stacked">
      <li><a href="#format">Format</a></li>
      <li><a href="#source">Source</a></li>
      <li><a href="#examples">Examples</a></li>
    </ul>

  </div>
</div>


      <footer>
      <div class="copyright">
  <p>Developed by Johannes Ranke.</p>
</div>

<div class="pkgdown">
  <p>Site built with <a href="https://pkgdown.r-lib.org/">pkgdown</a> 1.4.1.</p>
</div>

      </footer>
   </div>

  


  </body>
</html>


Contact - Imprint