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<meta property="og:description" content="This data set shows the response of the rat leukaemic cell line IPC-81 to
dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
February 25, 2004" />
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<h1>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</h1>
</div>
<p>This data set shows the response of the rat leukaemic cell line IPC-81 to
dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
February 25, 2004</p>
<pre class="usage"><span class='fu'>data</span>(<span class='no'>antifoul</span>)</pre>
<h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>
<p>A dataframe containing 135 and 81 data points for concentrations and responses
for TBT and Zink Pyrithione, respectively. Some additional columns from the
database are also present.</p>
<h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2>
<p><a href='http://www.uft.uni-bremen.de/chemie'>http://www.uft.uni-bremen.de/chemie</a></p>
<h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
<pre class="examples"><div class='input'><span class='no'>rantifoul.ED50</span> <span class='kw'><-</span> <span class='fu'>drfit</span>(<span class='no'>antifoul</span>,
<span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>weibull</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>,
<span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
<span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'>c</span>(<span class='fl'>10</span>))</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>TBT: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>Zn Pyrithion: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='input'><span class='fu'>print</span>(<span class='no'>rantifoul.ED50</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>5</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5%
#> 1 TBT 38 135 -2.7093 2.3979 linlogit -0.15809 -0.26021 -0.050475
#> 2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.26504 -0.056498
#> 3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.26116 -0.052591
#> 4 TBT 38 135 -2.7093 2.3979 weibull -0.11507 NA NA
#> 5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41329 -0.52932 -0.299799
#> 6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.50783 -0.291563
#> 7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.51049 -0.293501
#> 8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.38795 NA NA
#> unit sigma a b c ED50 ED50 2.5% ED50 97.5%
#> 1 microM 0.19264 -0.15809 1.04065 -0.024165 0.69487 0.54927 0.89028
#> 2 microM 0.19286 -0.16436 0.67637 NA 0.68493 0.54320 0.87801
#> 3 microM 0.19199 -0.16012 0.41358 NA 0.69164 0.54808 0.88595
#> 4 microM 0.18810 0.63743 1.28891 NA 0.76724 NA NA
#> 5 microM 0.22878 -0.41329 1.74249 0.610900 0.38611 0.29558 0.50142
#> 6 microM 0.22866 -0.39792 0.41696 NA 0.40002 0.31058 0.51102
#> 7 microM 0.22802 -0.40035 0.25395 NA 0.39779 0.30868 0.50874
#> 8 microM 0.23008 0.47647 2.51561 NA 0.40931 NA NA
#> EDx10
#> 1 0.085214
#> 2 0.093077
#> 3 0.085340
#> 4 0.053392
#> 5 0.120233
#> 6 0.116872
#> 7 0.110068
#> 8 0.121166</div><div class='input'>
<span class='no'>rantifoul.drc</span> <span class='kw'><-</span> <span class='fu'>drcfit</span>(<span class='no'>antifoul</span>,
<span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>weibull</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>,
<span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
<span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'>c</span>(<span class='fl'>10</span>))</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>TBT: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>Zn Pyrithion: Fitting data...</span></div><div class='input'><span class='fu'>print</span>(<span class='no'>rantifoul.drc</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>5</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5%
#> 1 TBT 38 135 -2.7093 2.3979 linlogit NA NA NA
#> 2 TBT 38 135 -2.7093 2.3979 probit -0.16436 -0.28178 -0.072022
#> 3 TBT 38 135 -2.7093 2.3979 logit -0.16012 -0.27782 -0.067603
#> 4 TBT 38 135 -2.7093 2.3979 weibull -0.13012 -0.23786 -0.043860
#> 5 Zn Pyrithion 27 81 -2.1072 2.0000 linlogit -0.41330 -0.54457 -0.312631
#> 6 Zn Pyrithion 27 81 -2.1072 2.0000 probit -0.39792 -0.52005 -0.302705
#> 7 Zn Pyrithion 27 81 -2.1072 2.0000 logit -0.40035 -0.52324 -0.304676
#> 8 Zn Pyrithion 27 81 -2.1072 2.0000 weibull -0.37351 -0.49792 -0.276917
#> unit sigma a b c ED50 ED50 2.5% ED50 97.5%
#> 1 microM 0.19264 0.71806 1.04061 -0.024169 NA NA NA
#> 2 microM 0.19286 0.68492 -0.64209 NA 0.68492 0.52267 0.84718
#> 3 microM 0.19199 0.69165 1.05007 NA 0.69165 0.52744 0.85585
#> 4 microM 0.18900 -0.13012 0.79816 NA 0.74111 0.57828 0.90394
#> 5 microM 0.22878 0.30926 1.74257 0.611358 0.38610 0.28538 0.48682
#> 6 microM 0.22866 0.40002 -1.04159 NA 0.40002 0.30196 0.49808
#> 7 microM 0.22802 0.39779 1.71015 NA 0.39779 0.29975 0.49582
#> 8 microM 0.23077 -0.37351 1.19152 NA 0.42315 0.31775 0.52855
#> EDx10 EDx10 2.5% EDx10 97.5%
#> 1 NA NA NA
#> 2 0.093074 0.040308 0.14584
#> 3 0.085338 0.035963 0.13471
#> 4 0.069958 0.026197 0.11372
#> 5 0.120238 0.043513 0.19696
#> 6 0.116878 0.048151 0.18561
#> 7 0.110068 0.043085 0.17705
#> 8 0.087066 0.017958 0.15617</div></pre>
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