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<title>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells — antifoul • drfit</title>


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<meta property="og:description" content="This data set shows the response of the rat leukaemic cell line IPC-81 to
  dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
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    <h1>Dose-Response data for TBT and Zink Pyrithione in IPC-81 cells</h1>
    
    <div class="hidden name"><code>antifoul.Rd</code></div>
    </div>

    <div class="ref-description">
    <p>This data set shows the response of the rat leukaemic cell line IPC-81 to
  dilution series of tributyltin chloride (TBT) and Zink Pyrithione as retrieved
  from the "cytotox" database of the UFT Department of Bioorganic Chemistry on
  February 25, 2004</p>
    </div>

    <pre class="usage"><span class='fu'><a href='https://rdrr.io/r/utils/data.html'>data</a></span>(<span class='no'>antifoul</span>)</pre>


    <h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>

    <p>A dataframe containing 135 and 81 data points for concentrations and responses
  for TBT and Zink Pyrithione, respectively. Some additional columns from the
  database are also present.</p>

    <h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
    <pre class="examples"><div class='input'><span class='no'>rantifoul.ED50</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drfit.html'>drfit</a></span>(<span class='no'>antifoul</span>,
                        <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>weibull</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>,
                        <span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
                        <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span>(<span class='fl'>10</span>))</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>TBT: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>Zn Pyrithion: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#&gt; <span class='message'>Waiting for profiling to be done...</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span>(<span class='no'>rantifoul.ED50</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>5</span>)</div><div class='output co'>#&gt;      Substance ndl   n     lld    lhd    mtype  logED50     2.5%     97.5%
#&gt; 1          TBT  38 135 -2.7093 2.3979 linlogit -0.15809 -0.26021 -0.050475
#&gt; 2          TBT  38 135 -2.7093 2.3979   probit -0.16436 -0.26504 -0.056498
#&gt; 3          TBT  38 135 -2.7093 2.3979    logit -0.16012 -0.26116 -0.052591
#&gt; 4          TBT  38 135 -2.7093 2.3979  weibull -0.11507       NA        NA
#&gt; 5 Zn Pyrithion  27  81 -2.1072 2.0000 linlogit -0.41329 -0.52932 -0.299799
#&gt; 6 Zn Pyrithion  27  81 -2.1072 2.0000   probit -0.39792 -0.50783 -0.291563
#&gt; 7 Zn Pyrithion  27  81 -2.1072 2.0000    logit -0.40035 -0.51049 -0.293501
#&gt; 8 Zn Pyrithion  27  81 -2.1072 2.0000  weibull -0.38795       NA        NA
#&gt;     unit   sigma        a       b         c    ED50 ED50 2.5% ED50 97.5%
#&gt; 1 microM 0.19264 -0.15809 1.04065 -0.024165 0.69487   0.54927    0.89028
#&gt; 2 microM 0.19286 -0.16436 0.67637        NA 0.68493   0.54320    0.87801
#&gt; 3 microM 0.19199 -0.16012 0.41358        NA 0.69164   0.54808    0.88595
#&gt; 4 microM 0.18810  0.63743 1.28891        NA 0.76724        NA         NA
#&gt; 5 microM 0.22878 -0.41329 1.74249  0.610900 0.38611   0.29558    0.50142
#&gt; 6 microM 0.22866 -0.39792 0.41696        NA 0.40002   0.31058    0.51102
#&gt; 7 microM 0.22802 -0.40035 0.25395        NA 0.39779   0.30868    0.50874
#&gt; 8 microM 0.23008  0.47647 2.51561        NA 0.40931        NA         NA
#&gt;      EDx10
#&gt; 1 0.085214
#&gt; 2 0.093077
#&gt; 3 0.085340
#&gt; 4 0.053392
#&gt; 5 0.120233
#&gt; 6 0.116872
#&gt; 7 0.110068
#&gt; 8 0.121166</div><div class='input'>
<span class='no'>rantifoul.drc</span> <span class='kw'>&lt;-</span> <span class='fu'><a href='drcfit.html'>drcfit</a></span>(<span class='no'>antifoul</span>,
                        <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>logit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>weibull</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>,
                        <span class='kw'>chooseone</span> <span class='kw'>=</span> <span class='fl'>FALSE</span>,
                        <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fu'><a href='https://rdrr.io/r/base/c.html'>c</a></span>(<span class='fl'>10</span>))</div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>TBT: Fitting data...</span></div><div class='output co'>#&gt; <span class='message'></span>
#&gt; <span class='message'>Zn Pyrithion: Fitting data...</span></div><div class='input'><span class='fu'><a href='https://rdrr.io/r/base/print.html'>print</a></span>(<span class='no'>rantifoul.drc</span>, <span class='kw'>digits</span> <span class='kw'>=</span> <span class='fl'>5</span>)</div><div class='output co'>#&gt;      Substance ndl   n     lld    lhd    mtype  logED50     2.5%     97.5%
#&gt; 1          TBT  38 135 -2.7093 2.3979 linlogit       NA       NA        NA
#&gt; 2          TBT  38 135 -2.7093 2.3979   probit -0.16436 -0.28178 -0.072022
#&gt; 3          TBT  38 135 -2.7093 2.3979    logit -0.16012 -0.27782 -0.067603
#&gt; 4          TBT  38 135 -2.7093 2.3979  weibull -0.13012 -0.23786 -0.043860
#&gt; 5 Zn Pyrithion  27  81 -2.1072 2.0000 linlogit -0.41330 -0.54457 -0.312631
#&gt; 6 Zn Pyrithion  27  81 -2.1072 2.0000   probit -0.39792 -0.52005 -0.302705
#&gt; 7 Zn Pyrithion  27  81 -2.1072 2.0000    logit -0.40035 -0.52324 -0.304676
#&gt; 8 Zn Pyrithion  27  81 -2.1072 2.0000  weibull -0.37351 -0.49792 -0.276917
#&gt;     unit   sigma        a        b         c    ED50 ED50 2.5% ED50 97.5%
#&gt; 1 microM 0.19264  0.71806  1.04061 -0.024169      NA        NA         NA
#&gt; 2 microM 0.19286  0.68492 -0.64209        NA 0.68492   0.52267    0.84718
#&gt; 3 microM 0.19199  0.69165  1.05007        NA 0.69165   0.52744    0.85585
#&gt; 4 microM 0.18900 -0.13012  0.79816        NA 0.74111   0.57828    0.90394
#&gt; 5 microM 0.22878  0.30926  1.74257  0.611358 0.38610   0.28538    0.48682
#&gt; 6 microM 0.22866  0.40002 -1.04159        NA 0.40002   0.30196    0.49808
#&gt; 7 microM 0.22802  0.39779  1.71015        NA 0.39779   0.29975    0.49582
#&gt; 8 microM 0.23077 -0.37351  1.19152        NA 0.42315   0.31775    0.52855
#&gt;      EDx10 EDx10 2.5% EDx10 97.5%
#&gt; 1       NA         NA          NA
#&gt; 2 0.093074   0.040308     0.14584
#&gt; 3 0.085338   0.035963     0.13471
#&gt; 4 0.069958   0.026197     0.11372
#&gt; 5 0.120238   0.043513     0.19696
#&gt; 6 0.116878   0.048151     0.18561
#&gt; 7 0.110068   0.043085     0.17705
#&gt; 8 0.087066   0.017958     0.15617</div></pre>
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