aboutsummaryrefslogtreecommitdiff
path: root/man/drfit.Rd
diff options
context:
space:
mode:
author(no author) <(no author)@d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc>2004-07-27 07:36:01 +0000
committer(no author) <(no author)@d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc>2004-07-27 07:36:01 +0000
commit8154a03c79eb910c42dcff03fd8fa611cdc8cc9d (patch)
treec4e64967d78078a0fb0a8c9ec85307c35c9ec8f9 /man/drfit.Rd
First version published on CRAN
git-svn-id: http://kriemhild.uft.uni-bremen.de/svn/drfit@1 d1b72e20-2ee0-0310-a1c4-ad5adbbefcdc
Diffstat (limited to 'man/drfit.Rd')
-rw-r--r--man/drfit.Rd59
1 files changed, 59 insertions, 0 deletions
diff --git a/man/drfit.Rd b/man/drfit.Rd
new file mode 100644
index 0000000..6e39032
--- /dev/null
+++ b/man/drfit.Rd
@@ -0,0 +1,59 @@
+\name{drfit}
+\alias{drfit}
+\title{Fit dose-response models}
+\description{
+ Fit dose-response relationships to dose-response data and calculate
+ biometric results for (eco)toxicity evaluation
+}
+\usage{
+ drfit(data, startlogEC50 = NA, lognorm = TRUE, logis = FALSE,
+ linearlogis = FALSE, b0 = 2, f0 = 0)
+}
+\arguments{
+ \item{data}{
+ A data frame as returned from \code{\link{drdata}}. The data frame has to
+ contain at least a factor called "substance", a vector called "unit"
+ containing the unit used for the dose, a column "response" with the
+ response values of the test system normalized between 0 and 1 and a column
+ "dose" with the numeric dose values. For later use of the
+ \code{\link{drplot}} function, a factor called "dosefactor" also has to be
+ present, containing the dose as a factor.
+ }
+ \item{startlogEC50}{
+ Especially for the linearlogis model, a suitable log10 of the EC50 has to be given
+ by the user, since it is not correctly estimated for data showing hormesis with
+ the default estimation method.}
+ \item{lognorm}{
+ A boolean defining if cumulative density curves of normal distributions
+ are fitted to the data. Default ist TRUE.}
+ \item{logis}{
+ A boolean defining if cumulative densitiy curves of logistic distributions
+ are fitted to the data. Default is FALSE.}
+ \item{linearlogis}{
+ A boolean defining if the linear-logistic function as defined by van Ewijk and Hoekstra
+ 1993 is fitted to the data. Default is FALSE.}
+ \item{b0,f0}{
+ If the linearlogistic model is fitted, b0 and f0 give the possibility to
+ adapt the starting values for the parameters b and f.}
+}
+\value{
+ \item{results}{
+ A data frame containing at least one line for each substance. If the data did not
+ show a mean response < 0.5 at the highest dose level, the modeltype is set to "none".
+ Every successful fit is reported in one line. Parameters of the fitted curves are only
+ reported if the fitted EC50 is not higher than the highest dose.}
+
+}
+\examples{
+\dontrun{data(antifoul)}
+\dontrun{r <- drfit(antifoul)}
+\dontrun{format(r,digits=2)}
+}
+\author{
+ Johannes Ranke
+ \email{jranke@uni-bremen.de}
+ \url{http://www.uft.uni-bremen.de/chemie/ranke}
+}
+\keyword{models}
+\keyword{regression}
+\keyword{nonlinear}

Contact - Imprint