aboutsummaryrefslogtreecommitdiff
path: root/tests/testthat/summary_saem_biphasic_s.txt
diff options
context:
space:
mode:
authorJohannes Ranke <jranke@uni-bremen.de>2022-03-07 12:03:40 +0100
committerJohannes Ranke <jranke@uni-bremen.de>2022-03-07 14:55:21 +0100
commit7035cde3a53781721fe15a8893fdf328c789bdd2 (patch)
treea1e4929faf9d645caedc0ed4dcc5036252497c63 /tests/testthat/summary_saem_biphasic_s.txt
parent77c248ca40b82ec00a756cd82f12968131f78959 (diff)
Remove nlmixr interface for release of mkin 1.1.0
I am postponing my attempts to get the nlmixr interface to CRAN, given some problems with nlmixr using R-devel under Windows, see https://github.com/nlmixrdevelopment/nlmixr/issues/596 and https://github.com/r-hub/rhub/issues/512, which is fixed by the removal of nlmixr from the testsuite. For the tests to be more platform independent, the biphasic mixed effects models test dataset was defined in a way that fitting should be more robust (less ill-defined).
Diffstat (limited to 'tests/testthat/summary_saem_biphasic_s.txt')
-rw-r--r--tests/testthat/summary_saem_biphasic_s.txt40
1 files changed, 20 insertions, 20 deletions
diff --git a/tests/testthat/summary_saem_biphasic_s.txt b/tests/testthat/summary_saem_biphasic_s.txt
index a353d821..6b203991 100644
--- a/tests/testthat/summary_saem_biphasic_s.txt
+++ b/tests/testthat/summary_saem_biphasic_s.txt
@@ -13,7 +13,7 @@ d_m1/dt = + f_parent_to_m1 * ((k1 * g * exp(-k1 * time) + k2 * (1 - g)
exp(-k2 * time))) * parent - k_m1 * m1
Data:
-507 observations of 2 variable(s) grouped in 15 datasets
+510 observations of 2 variable(s) grouped in 15 datasets
Model predictions using solution type analytical
@@ -24,7 +24,7 @@ Variance model: Two-component variance function
Mean of starting values for individual parameters:
parent_0 k_m1 f_parent_to_m1 k1 k2
- 1e+02 5e-03 5e-01 6e-02 1e-02
+ 1e+02 7e-03 5e-01 1e-01 2e-02
g
5e-01
@@ -35,37 +35,37 @@ Results:
Likelihood computed by importance sampling
AIC BIC logLik
- 2369 2379 -1170
+ 2334 2344 -1153
Optimised parameters:
est. lower upper
parent_0 1e+02 1e+02 1e+02
-k_m1 5e-03 4e-03 6e-03
+k_m1 7e-03 6e-03 7e-03
f_parent_to_m1 5e-01 4e-01 5e-01
-k1 6e-02 5e-02 7e-02
-k2 1e-02 9e-03 1e-02
-g 5e-01 4e-01 5e-01
+k1 1e-01 9e-02 1e-01
+k2 2e-02 2e-02 3e-02
+g 5e-01 5e-01 5e-01
Correlation:
pr_0 k_m1 f___ k1 k2
-k_m1 -0.3
-f_parent_to_m1 -0.3 0.3
-k1 0.1 -0.1 -0.1
+k_m1 -0.2
+f_parent_to_m1 -0.3 0.1
+k1 0.1 0.0 0.0
k2 0.0 0.0 0.0 0.1
-g 0.1 -0.1 0.0 -0.3 -0.3
+g 0.1 -0.1 0.0 -0.2 -0.2
Random effects:
est. lower upper
-SD.parent_0 0.02 -89.53 89.6
-SD.k_m1 0.20 0.07 0.3
-SD.f_parent_to_m1 0.32 0.20 0.4
-SD.k1 0.38 0.23 0.5
-SD.k2 0.33 0.20 0.5
-SD.g 0.26 0.06 0.5
+SD.parent_0 0.03 -49.24 49.3
+SD.k_m1 0.23 0.13 0.3
+SD.f_parent_to_m1 0.30 0.19 0.4
+SD.k1 0.40 0.25 0.5
+SD.k2 0.34 0.21 0.5
+SD.g 0.21 0.06 0.4
Variance model:
est. lower upper
-a.1 0.90 0.76 1.03
+a.1 0.93 0.79 1.06
b.1 0.05 0.05 0.06
Resulting formation fractions:
@@ -75,5 +75,5 @@ parent_sink 0.5
Estimated disappearance times:
DT50 DT90 DT50back DT50_k1 DT50_k2
-parent 26 146 44 12 60
-m1 144 478 NA NA NA
+parent 13 73 22 6 32
+m1 105 348 NA NA NA

Contact - Imprint