blob: 195d9e5b95175cca5cd43f185e847edc45122b4b (
plain) (
blame)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
|
Loading mkin
Loading required package: testthat
Loading required package: minpack.lm
Loading required package: rootSolve
Loading required package: inline
Loading required package: methods
Loading required package: parallel
Testing mkin
Calculation of FOCUS chi2 error levels: ..
Results for FOCUS D established in expertise for UBA (Ranke 2014): ......
The t-test for significant difference from zero: ..
Fitting the FOMC model with large parameter correlation: Model cost at call 1 : 2154.97
Model cost at call 2 : 2154.97
Model cost at call 4 : 2154.97
Model cost at call 5 : 388.1874
Model cost at call 9 : 198.5808
Model cost at call 10 : 198.5806
Model cost at call 13 : 167.315
Model cost at call 15 : 167.315
Model cost at call 17 : 122.5165
Model cost at call 21 : 110.3697
Model cost at call 25 : 99.37279
Model cost at call 26 : 99.37279
Model cost at call 29 : 85.86611
Model cost at call 30 : 85.86609
Model cost at call 33 : 83.79827
Model cost at call 35 : 83.79825
Model cost at call 37 : 77.76253
Model cost at call 39 : 77.76252
Model cost at call 40 : 77.76252
Model cost at call 41 : 74.85232
Model cost at call 45 : 71.0713
Model cost at call 49 : 69.0689
Model cost at call 53 : 65.69063
Model cost at call 54 : 65.69063
Model cost at call 57 : 63.81175
Model cost at call 58 : 63.81174
Model cost at call 61 : 61.77925
Model cost at call 65 : 60.68903
Model cost at call 69 : 58.787
Model cost at call 73 : 57.79498
Model cost at call 77 : 56.72184
Model cost at call 78 : 56.72184
Model cost at call 81 : 56.27078
Model cost at call 82 : 56.27077
Model cost at call 85 : 55.76643
Model cost at call 89 : 55.06746
Model cost at call 93 : 54.77276
Model cost at call 97 : 54.46435
Model cost at call 101 : 53.97206
Model cost at call 105 : 53.7466
Model cost at call 109 : 53.45331
Model cost at call 113 : 53.15008
Model cost at call 117 : 52.8698
Model cost at call 122 : 52.79044
Model cost at call 126 : 52.64587
Model cost at call 127 : 52.56412
Model cost at call 131 : 52.37304
Model cost at call 135 : 52.29005
Model cost at call 139 : 52.20652
Model cost at call 143 : 52.05187
Model cost at call 147 : 51.95367
Model cost at call 151 : 51.80296
Model cost at call 152 : 51.80296
Model cost at call 153 : 51.80296
Model cost at call 155 : 51.79287
Model cost at call 156 : 51.79286
Model cost at call 157 : 51.79286
Model cost at call 159 : 51.71749
Model cost at call 163 : 51.69885
Model cost at call 164 : 51.66416
Model cost at call 169 : 51.61289
Model cost at call 173 : 51.5739
Model cost at call 177 : 51.5122
Model cost at call 181 : 51.44598
Model cost at call 185 : 51.42107
Model cost at call 189 : 51.37519
Model cost at call 193 : 51.32105
Model cost at call 194 : 51.32105
Model cost at call 195 : 51.32105
Model cost at call 197 : 51.29233
Model cost at call 199 : 51.29233
Model cost at call 200 : 51.29233
Model cost at call 202 : 51.27541
Model cost at call 206 : 51.24732
Model cost at call 210 : 51.20348
Model cost at call 214 : 51.1884
Model cost at call 218 : 51.15654
Model cost at call 222 : 51.12473
Model cost at call 226 : 51.1093
Model cost at call 230 : 51.09604
Model cost at call 234 : 51.07288
Model cost at call 238 : 51.04678
Model cost at call 243 : 51.03801
Model cost at call 247 : 51.02297
Model cost at call 248 : 51.01588
Model cost at call 252 : 50.99353
Model cost at call 253 : 50.99353
Model cost at call 254 : 50.99353
Model cost at call 256 : 50.98775
Model cost at call 257 : 50.97537
Model cost at call 258 : 50.97537
Model cost at call 259 : 50.97537
Model cost at call 260 : 50.97537
Model cost at call 262 : 50.97142
Model cost at call 266 : 50.96632
Model cost at call 272 : 50.9654
Model cost at call 276 : 50.96385
Model cost at call 279 : 50.96385
Model cost at call 284 : 50.96354
Model cost at call 286 : 50.96354
Model cost at call 290 : 50.96292
Model cost at call 293 : 50.96292
Model cost at call 298 : 50.9628
Model cost at call 300 : 50.9628
Model cost at call 305 : 50.96277
Model cost at call 307 : 50.96277
Model cost at call 312 : 50.96277
Model cost at call 314 : 50.96277
Model cost at call 318 : 50.96276
Model cost at call 321 : 50.96276
Model cost at call 326 : 50.96276
Model cost at call 328 : 50.96276
Model cost at call 332 : 50.96275
Model cost at call 333 : 50.96274
Model cost at call 336 : 50.96274
Model cost at call 337 : 50.96274
Model cost at call 342 : 50.96274
Model cost at call 344 : 50.96274
Model cost at call 348 : 50.96274
Model cost at call 351 : 50.96274
Model cost at call 357 : 50.96274
Model cost at call 359 : 50.96274
Model cost at call 363 : 50.96274
Model cost at call 364 : 50.96274
Model cost at call 367 : 50.96274
Model cost at call 375 : 50.96274
Model cost at call 381 : 50.96274
Model cost at call 388 : 50.96274
Model cost at call 452 : 50.96274
.Model cost at call 1 : 2154.97
Model cost at call 3 : 2154.97
Model cost at call 5 : 2154.97
Model cost at call 6 : 716.4083
Model cost at call 8 : 716.4082
Model cost at call 11 : 136.1354
Model cost at call 12 : 136.1354
Model cost at call 15 : 64.35183
Model cost at call 16 : 64.35183
Model cost at call 20 : 61.48715
Model cost at call 22 : 61.48715
Model cost at call 24 : 59.59792
Model cost at call 26 : 59.59792
Model cost at call 28 : 57.47603
Model cost at call 30 : 57.47603
Model cost at call 32 : 57.10469
Model cost at call 34 : 57.10468
Model cost at call 36 : 54.78942
Model cost at call 38 : 54.78942
Model cost at call 40 : 54.29399
Model cost at call 42 : 54.29399
Model cost at call 44 : 53.55295
Model cost at call 46 : 53.55294
Model cost at call 49 : 53.10239
Model cost at call 51 : 53.10239
Model cost at call 53 : 52.95095
Model cost at call 55 : 52.95095
Model cost at call 57 : 52.41198
Model cost at call 59 : 52.41198
Model cost at call 61 : 52.24816
Model cost at call 63 : 52.24816
Model cost at call 65 : 51.99669
Model cost at call 67 : 51.99669
Model cost at call 69 : 51.82092
Model cost at call 71 : 51.82092
Model cost at call 74 : 51.69389
Model cost at call 76 : 51.69389
Model cost at call 78 : 51.64468
Model cost at call 80 : 51.64468
Model cost at call 82 : 51.46367
Model cost at call 84 : 51.46366
Model cost at call 86 : 51.407
Model cost at call 88 : 51.407
Model cost at call 90 : 51.30871
Model cost at call 92 : 51.30871
Model cost at call 94 : 51.23556
Model cost at call 96 : 51.23556
Model cost at call 98 : 51.17829
Model cost at call 100 : 51.17829
Model cost at call 103 : 51.13498
Model cost at call 105 : 51.13498
Model cost at call 107 : 51.11419
Model cost at call 109 : 51.11419
Model cost at call 111 : 51.05405
Model cost at call 113 : 51.05405
Model cost at call 115 : 51.0096
Model cost at call 117 : 51.0096
Model cost at call 119 : 50.97496
Model cost at call 121 : 50.97496
Model cost at call 125 : 50.96419
Model cost at call 126 : 50.96419
Model cost at call 129 : 50.96365
Model cost at call 131 : 50.96365
Model cost at call 134 : 50.96354
Model cost at call 136 : 50.96354
Model cost at call 138 : 50.96333
Model cost at call 140 : 50.96333
Model cost at call 142 : 50.9629
Model cost at call 144 : 50.9629
Model cost at call 147 : 50.96282
Model cost at call 149 : 50.96282
Model cost at call 152 : 50.9628
Model cost at call 156 : 50.96277
Model cost at call 161 : 50.96276
Model cost at call 165 : 50.96275
Model cost at call 170 : 50.96274
Model cost at call 175 : 50.96274
Optimisation by method Marq successfully terminated.
.
Model predictions with mkinpredict: ...
Fitting of parent only models: .....................
Complex test case from Schaefer et al. (2007) Piacenza paper: ..
Results for synthetic data established in expertise for UBA (Ranke 2014): ....
Calculation of maximum time weighted average concentrations (TWAs): ...
DONE ===========================================================================
|
