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<title>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells — IM1xIPC81 • drfit</title>
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<meta property="og:title" content="Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells — IM1xIPC81" />
<meta property="og:description" content="This is the raw data documenting the influence of the alkyl
chain length in 3 position on the toxicity to the
promyelocytic leukemia rat cell line IPC-81. The substances
are named according to the UFT naming scheme of these
substances. IM13 BF4 means 1-methyl-3-propylimidazolium
tetrafluoroborate, IM14 BF4 means
1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10
BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
This is a subset (only the BF4 anion) of the data
shown in Figure 3 in Ranke et al. (2004)." />
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<h1>Dose-Response data for 1-methyl-3-alkylimidazolium tetrafluoroborates in IPC-81 cells</h1>
<div class="hidden name"><code>IM1xIPC81.Rd</code></div>
</div>
<div class="ref-description">
<p>This is the raw data documenting the influence of the alkyl
chain length in 3 position on the toxicity to the
promyelocytic leukemia rat cell line IPC-81. The substances
are named according to the UFT naming scheme of these
substances. IM13 BF4 means 1-methyl-3-propylimidazolium
tetrafluoroborate, IM14 BF4 means
1-methyl-3-butylimidazolium tetrafluoroborate and IM1-10
BF4 means 1-methyl-3-decylimidazolium tetrafluoroborate.
This is a subset (only the BF4 anion) of the data
shown in Figure 3 in Ranke et al. (2004).</p>
</div>
<pre class="usage"><span class='fu'>data</span>(<span class='no'>IM1xIPC81</span>)</pre>
<h2 class="hasAnchor" id="format"><a class="anchor" href="#format"></a>Format</h2>
<p>A dataframe containing the data as required for the
<code>drfit</code> function. An additional column contains
the tested organism (name of the cell line).</p>
<h2 class="hasAnchor" id="source"><a class="anchor" href="#source"></a>Source</h2>
<p>Ranke J, Mölter K, Stock F, Bottin-Weber U, Poczobutt J,
Hoffmann J, Ondruschka B, Filser J, Jastorff B (2004)
Biological effects of imidazolium ionic liquids with varying
chain lenghts in acute Vibrio fischeri and WST-1 cell
viability assays. Ecotoxicology and Environmental Safety
58(3) 396-404</p>
<h2 class="hasAnchor" id="examples"><a class="anchor" href="#examples"></a>Examples</h2>
<pre class="examples"><div class='input'> <span class='no'>rIM1xIPC81</span> <span class='kw'><-</span> <span class='fu'>drfit</span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#> <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='output co'>#> <span class='warning'>Warning: NaNs wurden erzeugt</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'>Waiting for profiling to be done...</span></div><div class='input'>
<span class='no'>rIM1xIPC81.drc</span> <span class='kw'><-</span> <span class='fu'>drcfit</span>(<span class='no'>IM1xIPC81</span>, <span class='kw'>linlogit</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>showED50</span> <span class='kw'>=</span> <span class='fl'>TRUE</span>, <span class='kw'>EDx</span> <span class='kw'>=</span> <span class='fl'>10</span>)</div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM13 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM14 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM15 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM16 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM17 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM18 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM19 BF4: Fitting data...</span></div><div class='output co'>#> <span class='message'></span>
#> <span class='message'>IM1-10 BF4: Fitting data...</span></div><div class='input'>
<span class='fu'>print</span>(<span class='no'>rIM1xIPC81</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma
#> 1 IM13 BF4 9 81 0.5918 3.000 inactive NA NA NA microM NA
#> 2 IM14 BF4 20 216 -0.0103 3.176 no fit NA NA NA microM NA
#> 3 IM15 BF4 9 135 0.5918 3.000 inactive NA NA NA microM NA
#> 4 IM16 BF4 9 108 0.5918 3.000 inactive NA NA NA microM NA
#> 5 IM17 BF4 9 81 0.5918 3.000 linlogit 2.5786 2.506 2.6617 microM 0.2376
#> 6 IM18 BF4 9 135 0.5918 3.000 linlogit 1.6806 1.623 1.7419 microM 0.2325
#> 7 IM19 BF4 9 81 0.5918 3.000 linlogit 1.6496 1.598 1.7031 microM 0.1453
#> 8 IM1-10 BF4 11 162 -0.0103 3.000 linlogit 0.7697 0.687 0.8544 microM 0.2988
#> a b c ED50 ED50 2.5% ED50 97.5% EDx10
#> 1 NA NA NA NA NA NA NA
#> 2 NA NA NA NA NA NA NA
#> 3 NA NA NA NA NA NA NA
#> 4 NA NA NA NA NA NA NA
#> 5 2.5786 2.300 0.01468 378.941 320.424 458.918 230.782
#> 6 1.6806 2.237 0.05719 47.930 41.973 55.194 27.367
#> 7 1.6496 1.977 0.10956 44.628 39.671 50.483 23.031
#> 8 0.7697 1.936 0.45809 5.884 4.864 7.152 2.835</div><div class='input'> <span class='fu'>print</span>(<span class='no'>rIM1xIPC81.drc</span>,<span class='kw'>digits</span><span class='kw'>=</span><span class='fl'>4</span>)</div><div class='output co'>#> Substance ndl n lld lhd mtype logED50 2.5% 97.5% unit sigma
#> 1 IM13 BF4 9 81 0.5918 3.000 inactive NA NA NA microM NA
#> 2 IM14 BF4 20 216 -0.0103 3.176 linlogit NA NA NA microM 0.1529
#> 3 IM15 BF4 9 135 0.5918 3.000 inactive NA NA NA microM NA
#> 4 IM16 BF4 9 108 0.5918 3.000 inactive NA NA NA microM NA
#> 5 IM17 BF4 9 81 0.5918 3.000 linlogit 2.5786 2.4935 2.6497 microM 0.2376
#> 6 IM18 BF4 9 135 0.5918 3.000 linlogit 1.6806 1.6168 1.7362 microM 0.2325
#> 7 IM19 BF4 9 81 0.5918 3.000 linlogit 1.6496 1.5940 1.6990 microM 0.1453
#> 8 IM1-10 BF4 11 162 -0.0103 3.000 linlogit 0.7697 0.6774 0.8458 microM 0.2988
#> a b c ED50 ED50 2.5% ED50 97.5% EDx10 EDx10 2.5%
#> 1 NA NA NA NA NA NA NA NA
#> 2 5.390e+15 0.3148 -0.0001736 NA NA NA NA NA
#> 3 NA NA NA NA NA NA NA NA
#> 4 NA NA NA NA NA NA NA NA
#> 5 1.281e+02 2.3001 0.0146821 378.964 311.555 446.372 230.790 202.915
#> 6 2.079e+01 2.2373 0.0571925 47.930 41.382 54.478 27.367 23.809
#> 7 1.342e+01 1.9773 0.1094542 44.630 39.260 50.000 23.036 20.614
#> 8 2.258e+00 1.9362 0.4580784 5.884 4.758 7.011 2.835 2.181
#> EDx10 97.5%
#> 1 NA
#> 2 NA
#> 3 NA
#> 4 NA
#> 5 258.665
#> 6 30.925
#> 7 25.459
#> 8 3.489</div></pre>
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